Bibliografia

Proceedings of the XXVth International Congress of Ophthalmology held in Rome, Italy P. PIVETTI PEZZI (1). G. CATARINELLI (1), A. MONCADA (1), S. PERRONE (2). S. FILIPPI (2). O.R. BARICORDI (2). A. SENSI (3), A. BALBONI (3), L. MELCHIORRI (3) and P. L. MATTIUZ (3) (1) Istituto di Oftalmologia, Università "La Sapienza" di Roma, Italy; (2) Clinica Oculistica Università di Padova, Italy (3)Istituto di Genetica Medica, Università di Ferrara, Italy HLA ANTIGENS AND BEHCET'S DISEASE IN ITALY The etiology of Behcet's disease (BD) is still unknown. but several items of evidence suggest an autoimmune basis with a genetic background. Indeed. immunogenetic factors controlling susceptibility to the disease are strongly suggested by the association between the HLA-B5…

J. Trace Elem. Electrolytes Health Dis. Vol. 3, 1989, pp. 209-212 A. Balboni, L. Melchiorri, (1) R. Vecchietti, (2) S. Perrone, A. Sensi, M. Venturi and O.R. Baricordi lstituto di Genetica Medica (1) Dipartimenro di Chimica, Università di Ferrara, (2) Clinica Oculistica, Università di Padova, Italy Summary We have observed a significant increase of zinc concentration in plasma and erythrocytes in a group of Italian Behcet patients, evidencing a rare hyperzinchcmic condition associated with the disease. The increased zinc level observed does not show any relation to the presence of therapy or with the impairment of the hlastogcnic response to HSVI, a specific cellular defect in Behcet disease, confirmed in the present study. The possible biological meanin…

O.R. Baricordi (1), S. Perrone (2), P. Pivetti Pezzi (3), A. Sensi (1), F. Filippi (2) G. Catarinelli (3), A. Balboni (1), L. Melchiorri (1) (1) lstituto di Genetica Medica - Università di Ferrara, (2) Clinica Oculistica - Università di Padova, (3) lstituto di Oftalmologia - Università "La sapienza", Roma. Introduction Clinical and immunological features suggest a viral etiology for Behcet's disease (BO), while the association with HLA determinants supports the hypothesis that immunogenic factors are involved. Although conflicting results have been obtained from virus isolation, recent reports further implicate a virus, namely HSV 1, in the etiology of BD [1-2]. More recently, specific antibody and cellular proliferative responses to HSV 1 were studied in BD patients [3…